DR SHIRLEY KWEE

PDRN Skin Booster

PDRN Skin Booster

PDRN Skin Booster Treatment - Polynucleotide Injections

PDRN skin booster treatments are polynucleotide-based injectable skin boosters designed to support skin repair, hydration, and overall skin quality at a cellular level. These treatments utilise polydeoxyribonucleotide (PDRN), a compound derived from purified salmon DNA, which is structurally compatible with human skin and commonly used in medical aesthetics to support tissue recovery and skin regeneration.

Unlike dermal fillers that focus on adding volume or altering facial contours, a PDRN skin booster works within the skin itself to support gradual improvements in texture, elasticity, and resilience. This makes it suitable for individuals seeking skin rejuvenation without visible volumisation.

What Is PDRN Skin Booster?

A PDRN skin booster refers to a polynucleotide-based injectable treatment that supports the skin’s natural repair processes. PDRN works by activating fibroblasts and supporting the extracellular matrix (ECM), creating a biological environment that encourages skin renewal from within. Through this mechanism, PDRN helps support collagen and elastin synthesis, improves hydration and elasticity, and moderates inflammatory responses within the skin.

Because of these properties, PDRN skin booster treatments are commonly incorporated into care plans for concerns such as early ageing changes, post-procedure recovery, acne scarring, under-eye skin quality, and overall skin rejuvenation.

Types of PDRN Skin Boosters

Polynucleotide-based skin boosters can be formulated differently depending on treatment area and skin concern. Your practitioner will recommend a suitable approach based on skin condition, sensitivity, and treatment goals.

PDRN I (Eye)

This formulation is designed for the delicate under-eye area, where skin is thinner and more prone to early ageing changes.

Suitable for:

Individuals with dark eye circles, fine lines, crepey under-eye skin, or mild eye fatigue.

Key benefits:

Supports hydration and elasticity in fragile skin, improves skin density, and helps refresh the appearance of tired-looking eyes without adding volume.

PDRN S (Scar)

This formulation focuses on skin repair and regeneration, particularly in areas where skin structure has been compromised.

Suitable for:

Acne scars, textural irregularities, enlarged pores, post-procedure recovery, or weakened skin barriers.

Key benefits:

Supports tissue repair, collagen remodelling, and gradual improvement in skin texture and strength. It may be incorporated into broader treatment plans involving microneedling or energy-based procedures.

PDRN Healer

This option is commonly used for full-face skin rejuvenation when overall skin quality is the primary concern.

Suitable for:

Dull or dehydrated skin, early ageing changes, uneven texture, or reduced skin elasticity.

Key benefits:

Supports collagen and elastin production, enhances hydration, and improves skin resilience over time, making it suitable for maintenance or preventive care.

PDRN HB

This formulation combines polynucleotides with enhanced hydrating components to support moisture balance and skin barrier recovery.

Suitable for:

Dry or dehydrated skin, sensitive or compromised skin, and individuals seeking skin recovery support.

Key benefits:

Helps improve skin hydration, supports barrier function, and enhances skin comfort and radiance.

How the PDRN Procedure Is Performed

Step 1: Consultation and Personalised Plan

A consultation is conducted to assess skin condition, concerns, and suitability. This step allows the practitioner to determine which PDRN skin booster formulation and treatment areas are appropriate.

Step 2: Skin Preparation

The treatment area is cleansed thoroughly. A topical numbing agent may be applied where appropriate to support comfort during the procedure.

Step 3: Injection Technique

The PDRN solution is administered using fine needles through micro-injections placed at specific depths within the skin. Injection patterns are adjusted based on treatment area and skin needs.

Step 4: Post-Procedure and Downtime

Following treatment, mild redness or swelling may be present. Most individuals resume daily activities shortly after, with aftercare guidance provided.

Possible Side Effects of PDRN Skin Booster

Redness and Swelling

Temporary redness or swelling at injection sites may occur and usually settles within a short period.

Injection Site Bumps

Small raised areas can appear immediately after treatment, particularly with micro-injection techniques. These typically resolve as the product disperses.

Bruising

Mild bruising may occur, especially in delicate areas or in individuals prone to bruising.

Temporary Sensitivity

Some individuals experience mild tenderness or sensitivity, which generally improves as the skin settles.

PDRN Skin Booster Aftercare and Recovery

Avoid Heat and Strenuous Activity

It is generally recommended to avoid intense exercise, saunas, or hot environments for a short period after treatment.

Gentle Skincare Only

Avoid exfoliating products or strong active ingredients until the skin feels settled. Gentle cleansing and moisturising are usually sufficient.

Sun Protection

Sun protection is advised as treated skin may be more sensitive following a PDRN skin booster procedure.

Follow Personalised Guidance

Aftercare advice may vary depending on treatment areas and formulation used. Individualised guidance will be provided.

Recommended Treatment Plan

A PDRN skin booster treatment plan typically involves a short series of sessions to support gradual skin improvement. Many individuals begin with 3 to 4 sessions spaced approximately 3 to 4 weeks apart.

Maintenance treatments may be recommended every 6 to 12 months, depending on skin condition and response. Improvements develop progressively as skin repair and regeneration processes take place.

Frequently Asked Questions

What is a PDRN skin booster and how does it work in the skin?

A PDRN skin booster is an injectable treatment that focuses on supporting skin repair and regeneration rather than altering facial structure or adding volume. It contains polydeoxyribonucleotide (PDRN), which is used in medical aesthetics to support cellular recovery and skin renewal processes.

Once injected into the skin, PDRN supports fibroblast activity and the extracellular matrix, creating an environment that encourages gradual improvements in skin texture, elasticity, and resilience. Because the treatment works with the skin’s natural repair mechanisms, changes tend to develop progressively rather than appearing immediately.

How is a PDRN skin booster different from other skin booster treatments?

While all skin booster treatments aim to improve skin quality, they differ in focus. Some boosters prioritise hydration, while others support structural skin repair. A PDRN skin booster is generally chosen when skin regeneration, recovery, or strengthening is a key concern.

Your practitioner may recommend different types of skin boosters depending on whether hydration, repair, or a combination approach is more suitable.

What skin concerns are commonly treated with a PDRN skin booster?

A PDRN skin booster may be considered for concerns such as early signs of ageing, acne scarring, uneven texture, post-procedure skin recovery, or under-eye skin quality. It is also sometimes incorporated into treatment plans for skin that appears weakened, dehydrated, or slow to recover.

What should I expect during and after a PDRN skin booster session?

A session typically takes around 30 to 45 minutes, including preparation and post-treatment guidance. The product is delivered through small injections placed within the skin, and comfort measures such as topical numbing may be used.

After treatment, mild redness, swelling, or small bumps at injection sites may be visible. These usually settle within a short period. Most individuals resume daily activities on the same day, although aftercare guidance is provided to support recovery.

How many sessions are usually needed for a PDRN skin booster?

The number of sessions varies depending on skin condition, treatment goals, and how the skin responds. Many individuals begin with a short series of sessions spaced a few weeks apart, followed by maintenance treatments as advised.

Because a PDRN skin booster works by supporting gradual skin regeneration, improvements tend to develop over time rather than immediately after a single session. Your practitioner will recommend a plan tailored to your skin.

Can a PDRN skin booster be combined with other treatments or skincare?

Yes, a PDRN skin booster may be incorporated into a broader treatment plan alongside other aesthetic procedures, depending on skin tolerance and recovery timelines. This may include energy-based treatments or other injectables as part of a structured approach.

Supportive skincare may also be recommended to complement treatment. You can explore clinic-related options on our products page and review available treatment categories.

How do I arrange a consultation for a PDRN skin booster in Singapore?

A consultation allows your practitioner to assess your skin, discuss concerns, and determine whether a PDRN skin booster is appropriate. You can arrange a visit through our contact page.

If you would like to learn more about the clinical approach we take at our medical aesthetics clinic in Singapore beforehand, you may also visit our about page.

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Ready for the experience?

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Ready for the experience?

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